Cavernous malformations, also called cavernous angiomas and cavernomas, are abnormal clusters of dilated blood vessels. These masses are made up of little pockets, called caverns. They are filled with blood and lined with a special layer of cells, called the endothelium. These malformations can cause seizures, stroke symptoms, hemorrhages and headache.
Ranging in size from microscopic to inches in diameter, cavernous malformations can be located anywhere in the body including the liver, rectum, kidney, eyes, nerves, spinal cord and brain. Those that develop in the brain or spinal cord, called cerebral cavernous malformations (CCM), are the most serious.
About one in 200 people have a cavernous malformation, affecting men and women almost equally and occurring in people of all races, sexes and ages. In some cases, these malformations may run in families and are inherited. The abnormality either occurs spontaneously, typically with one lesion or frequently, producing many lesions.
Our Approach to Cavernous Malformations
UCSF offers compassionate, cutting-edge care for cavernous malformations. The health care provider team may include several types of specialists to provide comprehensive screening, diagnosis and treatment.
UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.